Scleroderma Lung Fibrosis and Biologic Drugs
نویسندگان
چکیده
منابع مشابه
Fibrocytes in Scleroderma Lung Fibrosis
Systemic sclerosis (SSc) or “Scleroderma” is a disease characterized by cutaneous and visceral fibrosis that affects both the skin and internal organs. The worldwide prevalence ranges from 50-300 cases per million (Chifflot et al., 2008) and much of the morbidity in this population results from pulmonary complications. In fact, nearly 70% of scleroderma patients show some form of lung disease. ...
متن کاملRetroperitoneal fibrosis and scleroderma.
The association of retroperitoneal fibrosis and systemic sclerosis is reported from a patient positive for the HLA-B27 antigen. This appears to be the first report of such an association. Pathological features common to the 2 syndromes are discussed and the literature is reviewed.
متن کاملScleroderma and Lung CHAPTER 15
Scleroderma is a chronic systemic disease of unknown cause, affecting around 15 persons in one million inhabitants in all parts of the world, but most frequently women between 40–60 years of age. Until recently, scleroderma was considered to be a disease with gloomy prognosis and no cure. The general attitude has changed during last decades due to successful treatment of scleroderma renal crisi...
متن کاملCurcumin Mitigates Radiation-induced Lung Pneumonitis and Fibrosis in Rats
Radiation-induced lung injury is one of the most prominent factors that interfere with chest cancer radiotherapy, and poses a great threat to patients exposed to total body irradiation. Upregulation of pro-oxidant enzymes is one of the main mechanisms through which the late effects of ionizing radiation on lung injury can be exerted. Interleukin (IL)-4 and IL-13 are two important cytokines that...
متن کاملEndothelin and scleroderma lung disease.
Scleroderma-associated interstitial lung disease (SSc-ILD) occurs frequently and for many patients SSc-ILD is a significant complication of their disease. SSc-ILD is now one of the leading causes of death among patients with SSc. SSc-ILD, classified most often as a non-specific interstitial pneumonia, may culminate in interstitial pulmonary fibrosis and end-stage lung disease. Fibrosis in the l...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Rheumatology : Current Research
سال: 2012
ISSN: 2161-1149
DOI: 10.4172/2161-1149.s1-001